BDBM50193097 CHEMBL3940387

SMILES CC(C)c1n(C)nc2ccc(cc12)-c1ccnc(N[C@H]2CC[C@@H](CC2)NC2CCOCC2)n1

InChI Key InChIKey=LHIUZPIDLZYPRL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50193097   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193097(CHEMBL3940387)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged CDK9/cyclin T1 expressed in baculovirus infected Sf21 insect cells using CDK9ptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50193097(CHEMBL3940387)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-C(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193097(CHEMBL3940387)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK8/cyclin C (unknown origin) using RBER-CHKStide as substrate after 60 mins in presence of 33P-ATP by microbeta scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193097(CHEMBL3940387)
Affinity DataIC50: 246nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged CDK7/cyclin H/N-terminal GST-tagged MAT1 expressed in baculovirus infected Sf21 in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50193097(CHEMBL3940387)
Affinity DataIC50: 400nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed