BDBM50193305 CHEMBL3917283

SMILES COc1cc(cc(c1)-c1ccccc1)C(=O)N1CCC(=O)Nc2ccccc12

InChI Key InChIKey=KVWYSEGVHJLHNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193305   

TargetBromodomain-containing protein 4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50193305(CHEMBL3917283)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human His-tagged BRD4 BD1 (49 to 170 residues) using H-SGRGK(Ac)GGK(Ac)GLGK-(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate preincubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50193305(CHEMBL3917283)
Affinity DataIC50: 9.14E+3nMAssay Description:Inhibition of human BRD4 BD2 (342 to 460 residues) at 30 uM preincubated for 30 mins followed by substrate addition measured after 30 mins by TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed