BDBM50193762 (+)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::(-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-3-(3-cyanophenyl)urea::CHEMBL218997

SMILES O=C(NCCC[C@H]1C[C@H](Cc2ccccc2)CCN1)Nc1cccc(c1)C#N

InChI Key InChIKey=FFTNCZSASXDDKK-UHFFFAOYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50193762   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataIC50: 13nMAssay Description:Binding affinity to CCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataIC50: 644nMAssay Description:Binding affinity to CCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataIC50: 644nMAssay Description:Binding affinity to CCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataKi:  34nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataKi:  34nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataKi:  35nMAssay Description:Inhibition of 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataKi:  35nMAssay Description:Inhibition of 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataKi:  37nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50193762((+/-)1-(3-((2S,4R)-4-benzylpiperidin-2-yl)propyl)-...)
Affinity DataKi:  37nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed