BDBM50193795 34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethyl-2-oxopyrrolidin-1-yl)bicyclo[2.2.2]octane-1-carboxamide::CHEMBL218569

SMILES CC1(C)C(COc2ccc(cn2)C#N)CN(C1=O)C12CCC(CC1)(CC2)C(N)=O

InChI Key InChIKey=RIECCHAKVDPPHN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50193795   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193795(34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed