BDBM50193892 CHEMBL217961::N-(3-chlorophenyl)-7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-amine::US8481536, 346

SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3cccc(Cl)c3)nnc2c1

InChI Key InChIKey=MJHIDASBEUSGFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193892   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Targegen

Curated by ChEMBL
LigandPNGBDBM50193892(US8481536, 346 | CHEMBL217961 | N-(3-chlorophenyl)...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Targegen

Curated by ChEMBL
LigandPNGBDBM50193892(US8481536, 346 | CHEMBL217961 | N-(3-chlorophenyl)...)
Affinity DataIC50: 134nMT: 2°CAssay Description:Recombinant human c-Src or Yes (28 ng/well, Panvera/Invitrogen, Madison Wis.), ATP (3 μM), a tyrosine kinase substrate (PTK2, 250 μM, Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent