BDBM50194080 9a-(4-chlorobenzyl)-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3H-fluoren-3-one::CHEMBL216024

SMILES CC1=C2c3ccc(O)cc3CC2(Cc2ccc(Cl)cc2)CCC1=O

InChI Key InChIKey=VXUQQBKYGQBLBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194080   

TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194080(9a-(4-chlorobenzyl)-7-hydroxy-4-methyl-1,2,9,9a-te...)
Affinity DataIC50: 22nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194080(9a-(4-chlorobenzyl)-7-hydroxy-4-methyl-1,2,9,9a-te...)
Affinity DataIC50: 6.80E+3nMAssay Description:Binding affinity to wild type ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed