BDBM50194629 2-{4-[3-(2-benzoyl-4-ethyl-phenoxy)-butoxy]-phenoxy}-2-methyl-propionic acid::CHEMBL215582

SMILES CCc1ccc(OC(C)CCOc2ccc(OC(C)(C)C(O)=O)cc2)c(c1)C(=O)c1ccccc1

InChI Key InChIKey=ILHLGCBMPLPUEJ-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50194629   

LigandPNGBDBM50194629(2-{4-[3-(2-benzoyl-4-ethyl-phenoxy)-butoxy]-phenox...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdelta by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50194629(2-{4-[3-(2-benzoyl-4-ethyl-phenoxy)-butoxy]-phenox...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-[propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino]-propyl}-phenoxy)-propionic acid from human PPARgamma by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50194629(2-{4-[3-(2-benzoyl-4-ethyl-phenoxy)-butoxy]-phenox...)
Affinity DataEC50:  6nMAssay Description:Transactivation of human PPARgamma in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50194629(2-{4-[3-(2-benzoyl-4-ethyl-phenoxy)-butoxy]-phenox...)
Affinity DataEC50:  45nMAssay Description:Transactivation of human PPARdelta in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50194629(2-{4-[3-(2-benzoyl-4-ethyl-phenoxy)-butoxy]-phenox...)
Affinity DataEC50:  686nMAssay Description:Transactivation of human PPARalpha in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50194629(2-{4-[3-(2-benzoyl-4-ethyl-phenoxy)-butoxy]-phenox...)
Affinity DataIC50: 1.32E+3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalpha by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed