BDBM50194829 7-(2,4-difluorophenyl)-N-(1-ethylcyclopentyl)-2,3-dihydro-1H-1,4-diazepin-5-amine::CHEMBL373966

SMILES CCC1(CCCC1)N=C1CC(=NCCN1)c1ccc(F)cc1F

InChI Key InChIKey=XUDZCNCCVGKQSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194829   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194829(7-(2,4-difluorophenyl)-N-(1-ethylcyclopentyl)-2,3-...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194829(7-(2,4-difluorophenyl)-N-(1-ethylcyclopentyl)-2,3-...)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to rat 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194829(7-(2,4-difluorophenyl)-N-(1-ethylcyclopentyl)-2,3-...)
Affinity DataIC50: 27nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed