BDBM50194909 CHEMBL221252::N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(3-methoxyphenyl)picolinamide

SMILES COc1cccc(c1)-c1nc(cc(N)c1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=RVPVTOKNUYGICG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194909   

TargetMitogen-activated protein kinase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50194909(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(3-...)
Affinity DataIC50: 430nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50194909(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(3-...)
Affinity DataIC50: 430nMAssay Description:Inhibition of JNK1 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194909(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(3-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of JNK2 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed