BDBM50194910 CHEMBL374447::N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(pyridin-4-yl)picolinamide

SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(n2)-c2ccncc2)cc1

InChI Key InChIKey=FAUFFPCPZRRZKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194910   

TargetMitogen-activated protein kinase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50194910(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(py...)
Affinity DataIC50: 530nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50194910(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(py...)
Affinity DataIC50: 530nMAssay Description:Inhibition of JNK1 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194910(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(py...)
Affinity DataIC50: 660nMAssay Description:Inhibition of JNK2 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed