BDBM50195306 CHEMBL3979383

SMILES Cc1ccccc1\C=C\C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O

InChI Key InChIKey=IYNYVDXHLBFLIF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195306   

TargetBcl-2-like protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50195306(CHEMBL3979383)
Affinity DataKi:  210nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50195306(CHEMBL3979383)
Affinity DataKi:  830nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to MCL-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50195306(CHEMBL3979383)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of 5-FAM-Bid peptide binding to Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed