BDBM50195539 CHEMBL3926291

SMILES COc1cc(\C=C\C(=O)c2ccc3ccccc3c2)cc(I)c1OC

InChI Key InChIKey=OOCLSYBZQFWYMX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195539   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University Bayreuth

Curated by ChEMBL

LigandBDBM50195539(CHEMBL3926291)Copy SMILESCopy InChI

Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/9/2018
Entry Details Article
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TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL

LigandBDBM50195539(CHEMBL3926291)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/9/2018
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL