BDBM50195543 CHEMBL2236206

SMILES COc1cc(\C=C\C(=O)c2ccc3ccccc3c2)cc(OC)c1OC

InChI Key InChIKey=CHKCKZJOXKQZMG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50195543   

LigandPNGBDBM50195543(CHEMBL2236206)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetTrophozoite cysteine proteinase(malaria parasite P. falciparum)TBA
LigandPNGBDBM50195543(CHEMBL2236206)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Plasmodium falciparum W2 cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTrophozoite cysteine proteinase(malaria parasite P. falciparum)TBA
LigandPNGBDBM50195543(CHEMBL2236206)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Plasmodium falciparum W2 cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195543(CHEMBL2236206)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed