BDBM50195787 CHEMBL3959431

SMILES COC(=O)[C@@H]1CNC[C@H](C1)N(CC(C)C)C(=O)c1cnc(nc1NCc1ccco1)C(C)(C)C

InChI Key InChIKey=XWKPQIHEQDPCKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195787   

TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195787(CHEMBL3959431)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195787(CHEMBL3959431)
Affinity DataIC50: 10nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed