BDBM50195898 4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methylsulfonyl)piperazin-1-yl)-2,4,6-trioxo-hexahydropyrimidin-5-yl)methyl)benzamide::4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methylsulfonyl)piperazin-1-yl)-2,4,6-trioxohexahydropyrimidin-5-yl)methyl)benzamide::CHEMBL395880

SMILES Cc1cc(COc2ccc(cc2)C(=O)NCC2(N3CCN(CC3)S(C)(=O)=O)C(=O)NC(=O)NC2=O)c2ccccc2n1

InChI Key InChIKey=FMMBVZGWJZFRLY-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50195898   

LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi:  2.17E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi:  2.17E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi: >4.50E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi: >4.50E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi: >6.37E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50195898(4-((2-methylquinolin-4-yl)methoxy)-N-((5-(4-(methy...)
Affinity DataKi: >6.37E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed