BDBM50195945 2-[3-(1,1-dioxo-1-thiolan-3-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]acetamide::CHEMBL375224

SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4ccccc4n(C4CCS(=O)(=O)C4)c3=O)cc2C1

InChI Key InChIKey=MUJODSURWGPHBP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195945   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195945(2-[3-(1,1-dioxo-1-thiolan-3-yl)-2-oxo-2,3-dihydro-...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195945(2-[3-(1,1-dioxo-1-thiolan-3-yl)-2-oxo-2,3-dihydro-...)
Affinity DataIC50: 64nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed