BDBM50195959 CHEMBL385322::N-(2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-inden]-5'-yl)-2-(3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)acetamide

SMILES Cn1c2ccccc2n(CC(=O)Nc2ccc3CC4(Cc3c2)NC(=O)NC4=O)c1=O

InChI Key InChIKey=XHBCDCYMANXQCP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195959   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195959(N-(2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'...)
Affinity DataKi:  78nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195959(N-(2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'...)
Affinity DataIC50: 530nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed