BDBM50196581 CHEMBL252962::N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzylamino)-propyl]-4-dipropylsulfamoyl-butyramide

SMILES CCCN(CCC)S(=O)(=O)CCCC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1cccc(OC)c1

InChI Key InChIKey=FQTKIOCGHMSTMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196581   

TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196581(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 7.95E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196581(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed