BDBM50196687 1-(2,6-dichlorobenzyl)-3-(1H-indazol-5-yl)urea::1-(2,6-dichlorophenyl)-3-(3H-indazol-5-yl)urea::CHEMBL225224

SMILES Clc1cccc(Cl)c1CNC(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=HCDNKTJUMCHZJG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196687   

TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196687(1-(2,6-dichlorophenyl)-3-(3H-indazol-5-yl)urea | 1...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196687(1-(2,6-dichlorophenyl)-3-(3H-indazol-5-yl)urea | 1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50196687(1-(2,6-dichlorophenyl)-3-(3H-indazol-5-yl)urea | 1...)
Affinity DataIC50: 20nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed