BDBM50196898 ((2R,6S)-1-(4-chlorophenylsulfonyl)-6-phenylpiperidin-2-yl)methyl 4-(piperidin-1-yl)piperidine-1-carboxylate::(cis-1-(4-chlorophenylsulfonyl)-6-phenylpiperidin-2-yl)methyl 4-(piperidin-1-yl)piperidine-1-carboxylate::CHEMBL396543

SMILES Clc1ccc(cc1)S(=O)(=O)N1[C@@H](COC(=O)N2CCC(CC2)N2CCCCC2)CCC[C@H]1c1ccccc1

InChI Key InChIKey=LTKKMSORNDRROD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196898   

TargetAmyloid-beta precursor protein(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50196898(((2R,6S)-1-(4-chlorophenylsulfonyl)-6-phenylpiperi...)
Affinity DataIC50: 16nMAssay Description:Inhibition of gamma-secretaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50196898(((2R,6S)-1-(4-chlorophenylsulfonyl)-6-phenylpiperi...)
Affinity DataIC50: 16nMAssay Description:Inhibition of gamma secretase-mediated amyloid-beta peptid aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed