BDBM50197067 CHEMBL3913746

SMILES CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccnc(Cl)c2)n1

InChI Key InChIKey=AWNXKZVIZARMME-UHFFFAOYSA-N

Data  30 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50197067   

TargetPhosphatidylinositol 4-kinase alpha(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 4.07E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 3.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 4.93E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase type 2-beta(Homo sapiens)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 76nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.07E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 76nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 382nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.13E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 2.69E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 2.14E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 8.04E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human Vps34-Vps15 complex expressed in insect cells assessed as reduction in PtdIns phosphorylation in presence of gamma32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed