BDBM50197103 (2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine::CHEMBL384474

SMILES C1C[C@@H]([C@@H]1[C@@H](C(=O)O)N)C(=O)O

InChI Key InChIKey=SRAFHGOPGVYULO-UHFFFAOYSA-N

Data  5 KI

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197103   

TargetGlutamate receptor 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  330nMAssay Description:Binding affinity to full length rat GluA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity to rat GluA3-LBD (GluK3-S1S2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed