BDBM50197105 (2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine::CHEMBL384123

SMILES N[C@@H]([C@H]1CC[C@H]1C(O)=O)C(O)=O

InChI Key InChIKey=SRAFHGOPGVYULO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197105   

TargetExcitatory amino acid transporter 2(Human)
University of Berne

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 3(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Berne

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed