BDBM50197391 CHEMBL3907817

SMILES CC(=S)NCCCC[C@@H]1NC(=O)[C@H](Cc2csc3ccccc23)NC(=O)CCCCCCC(=O)NC[C@H](NC1=O)C(N)=O

InChI Key InChIKey=FUDBWEWPOFSOLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197391   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197391(CHEMBL3907817)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant human GST or His6-tagged SIRT1 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
LigandPNGBDBM50197391(CHEMBL3907817)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence of bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197391(CHEMBL3907817)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 12 mins in presence of bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed