BDBM50197521 CHEMBL3922351

SMILES Clc1ccc(cc1)S(=O)(=O)N(Nc1ccccc1)C(=O)Oc1ccc2CCCc2c1

InChI Key InChIKey=DEFZOWRYMRTWHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197521   

TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197521(CHEMBL3922351)
Affinity DataIC50: 550nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197521(CHEMBL3922351)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197521(CHEMBL3922351)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed