BDBM50197592 CHEMBL397532::N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahydro-1H-5,11-diaza-benzo[a]trinden-8-yl)-thiazol-2-ylmethyl]-butyramide

SMILES CCCC(=O)NCc1nc(cs1)-c1ccc2[nH]c3c4CCCc4c4C(=O)NC(=O)c4c3c2c1

InChI Key InChIKey=VWVYKQCGYQYSBY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197592   

TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197592(N-[4-(4,6-dioxo-2,3,4,5,6,11-hexahydro-1H-5,11-dia...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed