BDBM50197594 8-(2-isoxazol-5-yl-thiazol-4-yl)-1,2,3,11-tetrahydro-5,11-diaza-benzo[]trindene-4,6-dione::CHEMBL245558

SMILES O=C1NC(=O)c2c1c1CCCc1c1[nH]c3ccc(cc3c21)-c1csc(n1)-c1ccno1

InChI Key InChIKey=MUPYJWFHURBOHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197594   

TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50197594(8-(2-isoxazol-5-yl-thiazol-4-yl)-1,2,3,11-tetrahyd...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed