BDBM50197616 CHEMBL3930625

SMILES OC(=O)c1ccc(Nc2cc(N3CCN(CC3)C3CCCCC3)c3noc4-c5ccccc5C(=O)c2c34)cc1

InChI Key InChIKey=MMUWXZUTOXDAGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197616   

TargetBDNF/NT-3 growth factors receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50197616(CHEMBL3930625)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BDNF-stimulated TrkB phosphorylation in human U2OS cells by beta-galactosidase reporter gene based PathHunter profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50197616(CHEMBL3930625)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NT3-stimulated TrkC phosphorylation in human U2OS cells by beta-galactosidase reporter gene based PathHunter profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50197616(CHEMBL3930625)
Affinity DataIC50: 50nMAssay Description:Inhibition of NGF-stimulated TrkA phosphorylation in human U2OS cells by beta-galactosidase reporter gene based PathHunter profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed