BDBM50197977 4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-pyrazol-5-yl)-N-(3-(pyridin-4-yl)propyl)butanamide::CHEMBL392493

SMILES Clc1cc(Cl)cc(c1)-c1cc(CCCC(=O)NCCCc2ccncc2)n(n1)-c1ccc2ccccc2c1

InChI Key InChIKey=NDZSILKFSNYFNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197977   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197977(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197977(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50: 1.12E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed