BDBM50198024 16-(hydroxymethyl)-22-[(E)-2-(1H-imidazol-1-yl)ethenyl]-4,14,18-triazaheptacyclo[12.10.2.0^{2,6}.0^{7,26}.0^{8,13}.0^{18,25}.0^{19,24}]hexacosa-1(25),2(6),7(26),8,10,12,19(24),20,22-nonaen-3-one::CHEMBL388220

SMILES OCC1Cn2c3ccccc3c3c4CNC(=O)c4c4c5cc(\C=C\n6ccnc6)ccc5n(C1)c4c23

InChI Key InChIKey=LMWATYNKYSUDRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198024   

TargetTyrosine-protein kinase JAK3(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50198024(16-(hydroxymethyl)-22-[(E)-2-(1H-imidazol-1-yl)eth...)
Affinity DataIC50: 109nMAssay Description:Inhibition of JAK3 expressed in Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed