BDBM50198122 2-(2-amino-1,3-thiazol-4-yl)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-{spiro[indene-1,4'-piperidine]-1'-yl}butanamide::CHEMBL396517

SMILES Nc1nc(cs1)C(CCN1CCC2(CC1)C=Cc1ccccc21)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=XTYCUSYXJAWVFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198122   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198122(2-(2-amino-1,3-thiazol-4-yl)-N-{[3,5-bis(trifluoro...)
Affinity DataIC50: 7.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed