BDBM50198150 CHEMBL397749::N-(3,5-bis-trifluoromethyl-benzyl)-2-(2-guanidino-thiazol-4-yl)-4-(4-phenyl-piperidin-1-yl)-butyramide

SMILES [#7]\[#6](-[#7])=[#7]\c1nc(cs1)-[#6](-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1ccccc1)-[#6](=O)-[#7]-[#6]-c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=RKJLTRANSVHBHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198150   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198150(N-(3,5-bis-trifluoromethyl-benzyl)-2-(2-guanidino-...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed