BDBM50198164 CHEMBL3959577::US10479798, Compound 3

SMILES Cc1cc(=O)oc2c3C[C@H](N)[C@H](Oc3ccc12)c1cc(F)c(F)cc1F

InChI Key InChIKey=MXZDPLKXVPVWMV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198164   

TargetDipeptidyl peptidase 4(Human)
East China University of Science and Technology

US Patent
LigandPNGBDBM50198164(CHEMBL3959577 | US10479798, Compound 3)
Affinity DataIC50: 154nMAssay Description:Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2020
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
East China University of Science and Technology

US Patent
LigandPNGBDBM50198164(CHEMBL3959577 | US10479798, Compound 3)
Affinity DataIC50: 155nMAssay Description:Inhibition of DPP-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
East China University of Science and Technology

US Patent
LigandPNGBDBM50198164(CHEMBL3959577 | US10479798, Compound 3)
Affinity DataIC50: 155nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC peptide substrate assessed as increase in fluorescence for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
East China University of Science and Technology

US Patent
LigandPNGBDBM50198164(CHEMBL3959577 | US10479798, Compound 3)
Affinity DataIC50: 165nMAssay Description:Inhibition of DPP4 (unknown origin) expressed in Sf9 cells using Gly-Pro-AMC substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2018
Entry Details Article
PubMed