BDBM50198577 (S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(3-(trifluoromethyl)phenethyl)piperazin-2-one::4-(3-(trifluoromethyl)phenethyl)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one::CHEMBL214323

SMILES CCN(CC)Cc1ccc2C[C@H](CCc2c1)N1CCN(CCc2cccc(c2)C(F)(F)F)CC1=O

InChI Key InChIKey=MMYOYIKJFUXCPY-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198577   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198577((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198577((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198577((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  93nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198577((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  93nMAssay Description:Binding affinity at MCHR1 by flash plate radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed