BDBM50198580 4-{[(6S)-6-{4-[2-(4-fluorophenyl)ethyl]-2-oxopiperazin-1-yl}-5,6,7,8-tetrahydronaphthalen-2-yl]methyl}-1,4-thiomorpholine-1,1-dione::CHEMBL216959

SMILES Fc1ccc(CCN2CCN([C@H]3CCc4cc(CN5CCS(=O)(=O)CC5)ccc4C3)C(=O)C2)cc1

InChI Key InChIKey=PTWGVYYSUNMNEA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198580   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198580(4-{[(6S)-6-{4-[2-(4-fluorophenyl)ethyl]-2-oxopiper...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198580(4-{[(6S)-6-{4-[2-(4-fluorophenyl)ethyl]-2-oxopiper...)
Affinity DataKi:  9.40E+4nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed