BDBM50198668 CHEMBL3955372

SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(C#N)n1C

InChI Key InChIKey=KQOPRUXRGLXURF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198668   

TargetProgesterone receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198668(CHEMBL3955372)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198668(CHEMBL3955372)
Affinity DataIC50: 1.36E+3nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PR-LBD (675 to 933 residues) expressed in baculovirus-infected insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198668(CHEMBL3955372)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dexamethasone from human GR measured after 18 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed