BDBM50198673 CHEMBL3975572

SMILES Cc1cc(=O)oc2cc(O)c(cc12)-c1ccc(C#N)n1C

InChI Key InChIKey=SBSAZAWOVDYWIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198673   

TargetProgesterone receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198673(CHEMBL3975572)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50198673(CHEMBL3975572)
Affinity DataIC50: 1.57E+4nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PR-LBD (675 to 933 residues) expressed in baculovirus-infected insect cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2018
Entry Details Article
PubMed