BDBM50198946 CHEMBL232452::N-(1-(1H-indol-3-yl)propan-2-yl)-2,4,6-trimethylbenzenesulfonamide

SMILES Cc1cc(C)c(S(=O)(=O)NC(C)Cc2c[nH]c3ccccc23)c(C)c1

InChI Key InChIKey=VPBRSFFMKTUJNN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198946   

TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198946BDBM50198946(N-(1-(1H-indol-3-yl)propan-2-yl)-2,4,6-trimethylbe...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198946BDBM50198946(N-(1-(1H-indol-3-yl)propan-2-yl)-2,4,6-trimethylbe...)
Affinity DataIC50: 40nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198946BDBM50198946(N-(1-(1H-indol-3-yl)propan-2-yl)-2,4,6-trimethylbe...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human MRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50198946BDBM50198946(N-(1-(1H-indol-3-yl)propan-2-yl)-2,4,6-trimethylbe...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed