BDBM50199114 CHEMBL3966165

SMILES CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(C(=O)NCCOCCC(=O)NO)c(F)c1

InChI Key InChIKey=WJJUHRROKLXWDS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50199114   

TargetHistone deacetylase 6(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199114(CHEMBL3966165)
Affinity DataIC50: 495nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199114(CHEMBL3966165)
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199114(CHEMBL3966165)
Affinity DataIC50: 5.81E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199114(CHEMBL3966165)
Affinity DataIC50: 8.65E+4nMAssay Description:Inhibition of HDAC2 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199114(CHEMBL3966165)
Affinity DataIC50: 4.92E+4nMAssay Description:Inhibition of HDAC3 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed