BDBM50199607 (R)-4-(4-methoxyphenyl)-2-methyl-7-(3-((S)-3-methylmorpholino)propoxy)-1,2,3,4-tetrahydroisoquinoline::CHEMBL247161

SMILES COc1ccc(cc1)[C@H]1CN(C)Cc2cc(OCCCN3CCOC[C@@H]3C)ccc12

InChI Key InChIKey=DIMAAAZZSSXDEH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199607   

TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50199607((R)-4-(4-methoxyphenyl)-2-methyl-7-(3-((S)-3-methy...)
Affinity DataKi:  6nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50199607((R)-4-(4-methoxyphenyl)-2-methyl-7-(3-((S)-3-methy...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50199607((R)-4-(4-methoxyphenyl)-2-methyl-7-(3-((S)-3-methy...)
Affinity DataKi:  13nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed