BDBM50199626 CHEMBL401429::cis-1-(3-(benzyloxy)phenyl)-3-(3-((dimethylamino)methyl)cyclobutyl)imidazo[1,5-a]pyrazin-8-amine

SMILES CN(C)C[C@H]1C[C@H](C1)c1nc(-c2cccc(OCc3ccccc3)c2)c2c(N)nccn12

InChI Key InChIKey=VGKYCQHCDYKNJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199626   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199626(cis-1-(3-(benzyloxy)phenyl)-3-(3-((dimethylamino)m...)
Affinity DataIC50: 166nMAssay Description:Inhibition of human recombinant GST-IGF1R activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199626(cis-1-(3-(benzyloxy)phenyl)-3-(3-((dimethylamino)m...)
Affinity DataIC50: 191nMAssay Description:Inhibition of IGF1-stimulated phosphorylation of human recombinant IGF1R expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed