BDBM50199683 3-(8-amino-3-cyclobutylimidazo[1,5-a]pyrazin-1-yl)phenol::CHEMBL245407

SMILES Nc1nccn2c(nc(-c3cccc(O)c3)c12)C1CCC1

InChI Key InChIKey=FYHLIVYLLJCASJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199683   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199683(3-(8-amino-3-cyclobutylimidazo[1,5-a]pyrazin-1-yl)...)
Affinity DataIC50: 518nMAssay Description:Inhibition of human recombinant GST-IGF1R activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199683(3-(8-amino-3-cyclobutylimidazo[1,5-a]pyrazin-1-yl)...)
Affinity DataIC50: 520nMAssay Description:Inhibition of IGF-1R by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed