BDBM50199725 CHEMBL3985784

SMILES CCn1nc(cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O)-c1cccc(c1)-c1cc(cc(c1)C(=O)NC1CC1)C#N

InChI Key InChIKey=WAHWCSHGGQRVLA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50199725   

TargetAdenosine receptor A2b(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50199725(CHEMBL3985784)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at adenosine A2b receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50199725(CHEMBL3985784)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of human recombinant PDE4B1 assessed as reduction in [3H]cAMP hydrolysis to [3H]AMP incubated for 60 mins by PDE-SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2018
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50199725(CHEMBL3985784)
Affinity DataIC50: 634nMAssay Description:Antagonist activity at adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2018
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50199725(CHEMBL3985784)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at adenosine A2a receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2018
Entry Details Article
PubMed