BDBM50199961 3-(1-{2-[1-(1,4-dioxa-spiro[4.5]dec-2-yl)-3-hydroxy-propoxy]-ethyl}-1H-indol-3-yl)-4-(4-fluoro-1H-indol-3-yl)-pyrrole-2,5-dione::CHEMBL220456

SMILES OCCC(OCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3cccc(F)c23)c2ccccc12)C1COC2(CCCCC2)O1

InChI Key InChIKey=HNMGPKKHNFEUFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199961   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50199961(3-(1-{2-[1-(1,4-dioxa-spiro[4.5]dec-2-yl)-3-hydrox...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed