BDBM50200267 CHEMBL214668::[3',5'-difluoro-3-(1-phenyl-1H-pyrazole-4-carbonyl)biphenyl-4-yloxy]acetic acid

SMILES OC(=O)COc1ccc(cc1C(=O)c1cnn(c1)-c1ccccc1)-c1cc(F)cc(F)c1

InChI Key InChIKey=YJNAKVPVZRVYIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200267   

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200267([3',5'-difluoro-3-(1-phenyl-1H-pyrazole-4-carbonyl...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200267([3',5'-difluoro-3-(1-phenyl-1H-pyrazole-4-carbonyl...)
Affinity DataIC50: 147nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed