BDBM50200275 CHEMBL216366::ethyl 4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxyacetate

SMILES CCOC(=O)COc1ccc(Br)cc1C(=O)c1cnn(c1)-c1ccccc1

InChI Key InChIKey=KBXJQIDNYQTMNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200275   

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200275(ethyl 4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)p...)
Affinity DataIC50: 165nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200275(ethyl 4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)p...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed