BDBM50200503 CHEMBL67885

SMILES COc1ccc2C(=O)CC(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)NCc3c(F)cccc3F)c2c1

InChI Key InChIKey=XERVAQYNJKWPRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200503   

TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50200503(CHEMBL67885)
Affinity DataIC50: 140nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome (unknown origin) using succinyl-leu-leu-val-tyr-7-amino-4-methyl coumarin as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed