BDBM50200513 CHEMBL3899778

SMILES COc1ccc(NC(=O)C2CCN(CC2)C(=O)N[C@@H](CCc2ccccc2)C(=O)N[C@@H](CCc2ccccc2)C(=O)NCc2ccccc2Cl)cc1

InChI Key InChIKey=KDJMZKYMGGZIKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200513   

TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50200513(CHEMBL3899778)
Affinity DataIC50: 16nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome preincubated for 15 mins followed by addition of Suc-Leu-Leu-Val-Tyr-AMC as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2018
Entry Details Article
PubMed