BDBM50200652 (8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-17-hydroxy-17-(3-methoxy-prop-1-ynyl)-11,13-dimethyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one::CHEMBL428012

SMILES COCC#C[C@]1(O)CC[C@H]2[C@@H]3OCC4=CC(=O)CCC4=C3[C@](C)(C[C@]12C)c1ccc(cc1)N(C)C

InChI Key InChIKey=HFQCJPQBQUZNQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200652   

TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200652((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 315nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced GRE-linked luciferase reporter gene ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200652((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed