BDBM50200656 (8S,11R,13S,14R,17S)-17-cyclopropylethynyl-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one::CHEMBL428011

SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC2CC2)[C@@H]2OCC3=CC(=O)CCC3=C12

InChI Key InChIKey=XKWKJRMCRANYBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200656   

TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200656((8S,11R,13S,14R,17S)-17-cyclopropylethynyl-11-(4-d...)
Affinity DataIC50: 9.60nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200656((8S,11R,13S,14R,17S)-17-cyclopropylethynyl-11-(4-d...)
Affinity DataIC50: 33.4nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced GRE-linked luciferase reporter gene ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed